Composition and Specifications of the XPure-S SMB Chromatography System

  • Valve blocks dedicated to every single column, integrated to one valve block
  • Multiple pumps
  • Monitor and control system closing and opening valves based on time or sensors
  • Tubing between pumps, valve block, and columns
  • Minimum of 4 static columns, with maximum to 16 static columns configuration
SMB addition

The XPure-SE system offers expanded bed control for each individual column.

  • One pump every column
  • One Level Transmitter every column
  • One in-line strainer (resin trap) at every column outlet
  • Level control for all expanded bed zones, integrated in process control system

XPure-S & XPure-SE Technical Facts

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Flexible Control

Run 1–16 columns

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Wide Flow Range

Bench-top XPure-S: 2 – 3,000 mL/min

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Column Material and Size Match Process Application

PVC; PVDF; PTFE, glass or stainless steel, any other material possible
Internal Diameter: 5 – 300mm
Length: 100 – 1500mm

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Expanded Bed Mode

Optional (XPure-SE)

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Industrial Scale

XPure-S can be easily configured at an industrial level

Learn more about this configuration

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Ability to Run Multiple Processes

Batch process sequence can be programmed

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Robust Valve Block with high chemical resistance

5 inlets and 5 outlets
Max pressure: 5 barg / 75psig

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Integrated Online Instruments

Conductivity, pH, UV-VIS, and more

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Compact Footprint Bench-top system

4-8 column system: 760x600x330mm
Net weight: 75 kg

12-16 column system: 760x1200x330mm
Net weight: 150 kg

Improve purity and yield of target molecules to ensure high-quality ingredients for product manufacturers

See How

The XPure Advantage

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Easy to Use

XPure hardware and software are designed for easy operation and the flexibility to implement a wide range of process control strategies

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Scalable to Your Needs

Simple and modular multi-column hardware is designed to scale from lab or pilot to industrial scale

Service Excellence

Our team of experts is dedicated to providing cost effective purification process solutions tailored to your specific needs