Capture and Recovery from Complex Streams Without Requiring Clarification or Intensive Pre-Processing
EBA chromatography effectively addresses the critical challenges of packed bed chromatography. It eliminates the need for clarification, resulting in lower costs and improved yield. Minimal back pressure enables the user to achieve optimal scale of operation and productivity.
The XPure-E system is the only bench scale system available on the market for EBA. It is easy to install, use, and maintain for lab or pilot scale operations.
- Intuitive software with flexibility to use both EBA/PB mode
- Robust mechanicals that can process unclarified broth
- High degree of flexibility for both equipment and automation design
- Enables critical bed level control for EBA chromatography operation
Composition and Specifications of the XPure-E EBA Chromatography System
- Valve blocks dedicated to multiple buffer solutions
- System can operate with 1 or 2 pumps for stepwise dilution
- Intuitive recipe editor for a maximum of 12 successive steps
XPure-E Technical Facts
Ease of Operation
Touchscreen for process sequence programming
Wide Flow Range
Internal bore: 2 mm
Max flow: 2 – 300 ml/min
Integrated Column Sensor
For bed level detection
Integrated Monitoring Instruments
Conductivity, pH, flow pressure (inlet and outlet)
Optional: UV and temperature
Compact FootprintFlexible for lab scale operations
4-8 column system: 300(W)x300(D)x500(H) mm
Net weight: 25 kg
Robust Fluid Distribution System with high density ceramic beads
6 inlets and 4 outlets
Max pressure: 5 barg / 75psig
Max temperature: 60°C
Column Material and Size Match Process Application
PVC-U; PVDF; PTFE, glass or stainless steel, any other material possible
Internal Diameter: 10 – 25 mm
Length: 400-1000 mm
Or any dimension depending on the process
Flexible Tubing Options
Anything from PPE to PFA or PTFE
Outer diameter: 1/8 – 1/4” or metric sizes
Expanded Bed Mode
With online monitoring and smart bed level control
Improve purity and yield of target molecules to ensure high-quality ingredients for product manufacturers
See HowThe XPure Advantage
Easy to Use
XPure hardware and software are designed for easy operation and the flexibility to implement a wide range of process control strategies
Scalable to Your Needs
Simple and modular multi-column hardware is designed to scale from lab or pilot to industrial scale
Service Excellence
Our team of experts is dedicated to providing cost effective purification process solutions tailored to your specific needs