Continuous Chromatography
Made Easy

Choose XPure chromatography systems to develop easy to operate and flexible Simulated Moving Bed processes for your purification challenge.

XPure Advantage

The XPure Advantage

XPure Advantage

XPure is committed to improving separation efficiency by designing and delivering innovative, customized continuous ion exchange and chromatography systems.

XPure uniquely features expanded bed adsorption technology that is integrated in our SMB configured systems. This enables us to directly process particulates containing feed streams, for example from fermentation or plant based juice streams.

Our systems integrate modular and scalable simulated moving bed hardware with a smart and flexible software platform, enabling the flexibility to implement a wide range of process control strategies. This holistic approach reduces resin and solvent consumption and increases product concentrations, purity, and yields.

This singular focus on process technology and equipment means we are independent of resin and media suppliers. Rather, our team of experts deliver the suitable and cost-effective solutions to meet your separation requirements.

XPure enables the purification of bio-based chemicals and mild fractionation of food components using an efficient technology that contributes to a sustainable process industry.

More About XPURE

XPure Products & Services

XPure Systems offers a line of innovative SMB continuous chromatography and ion exchange systems that are specified to your applications and easily scalable. In addition, expert consulting is available to develop your products and support your manufacturing processes or optimize legacy separation processes.


From bench-top to industrial scale, XPure offers a variety of systems to meed your application needs


Service excellence delivered by expert consultants who focus on your specific application needs, including optimizing legacy systems

Latest News + See All News

Read the latest case studies, news, and blog posts related to protein purification, downstream processing, and SMB technology advances.